On February 2-4, 2018, members of the COMPPARE Consortium gathered at the beautiful Omni Amelia Island Plantation Resort in Amelia Island, FL, for a development workshop to prepare for the start of our PCORI contract on April 1. Dr. Nancy Mendenhall, the Principal Investigator (PI), and Dr. Ronald Chen, the co-PI, were joined by co-investigators from over 40 institutions, research coordinators, project managers, and insurance, patient, and minority engagement stakeholders to discuss best practices, accrual strategies, and patient engagement across the spectrum.